Columbia University
Department of Statistics

Research interests

Statistical genetics, Bioinformatics, Survival Analysis, Design of Clinical Trials, Resampling Methods, Coverage Problems, Analysis of Incomplete Data, Nonparametric Methods, Asymptotic Theory, and Empirical Bayes Methodology.

Recent publications

• Zheng T, Wang S, Cong L, Ding YJ, Ionita-Laza I, Lo SH (2006) Joint study of genetic regulators for Expression Traits Related to Breast Cancer. Genetic Analysis Workshop. In press.
• Ionita-Laza I, Ding YJ, Zheng T, Cong L, Lo SH (2006) Combined Linkage and Association Analysis of the NARAC Dataset. Genetic Analysis Workshop. In press.
• Ding YJ, Zheng T, Ionita-Laza I, Cong L, Lo SH (2006) Constructing Association Network in Two-Stage Analysis: An application of Backward Genotype-Trait Association (BGTA) Algorithm to NARAC Data. Genetic Analysis Workshop. In press.
• Cong L, Zheng T, Ionita-Laza I, Ding YJ, Lo SH (2006) A Comprehensive Analysis of Association between Several Candidate Genes and Rheumatoid Arthritis in Samples from North American Rheumatoid Arthritis Consortium (NARAC). Genetic Analysis Workshop. In press.
• Zheng T, Wang H, Lo SH (2006) Backward Genotype-Trait Association (BGTA)-Based Dissection of Complex Traits in Case-Control Designs. Human Heredity. In press.
• Zheng T, Lo SH (2006) A rank-based method for evaluating the reproducibility of studies with a large number of objects. Festschrift for Kjell Doksum. In press.
• Zheng T, Wang H, Lo SH (2005) Rank-based generalized genotype-trait association algorithm for the mapping of quantitative trait loci. Technical report.
• Yan X, Zheng T, Lo SH (2005) Discriminant Analysis using Multi-gene Profiles in Molecular Classification of Breast Cancer. Technical report.
• Ionita I, Lo SH (2005) Multilocus linkage analysis of affected sib pairs. Human Heredity 60:227-240
• Cespedes C, Miller M, Lo SH, Lowy FD (2005) Reply to Coen et al. Journal of Infectious Diseases 191:1993
• Cespedes C, Said-Salim B, Miller M, Lo SH, Kreiswirth BN, Gordon RJ, Vavagiakis P, Klein RS, Lowy FD (2005) The Clonality of Staphylococcus aureus Nasal Carriage. Journal of Infectious Diseases 191(3):444-52
• Lo SH, Zheng T (2004) A demonstration and findings of a statistical approach through reanalysis of inflammatory bowel disease data. Proc Natl Acad Sci U S A 101(28):10386-91
• Shane E, Addesso V, Namerow PB, McMahon DJ, Lo SH, Staron RB, Zucker M, Pardi S, Maybaum S, Mancini D (2004) Prevention of bone loss after cardiac transplantation: an NIH-sponsored randomized controlled clinical trial. New England Journal of Medicine 350:767-76
• Lo SH, Liu X, Shao YZ (2003) A statistical likelihood approach for family-based studies in human genetics. Ann. Hum. Genet. 67: 1-10
• Fan W, Wang H, Yu P, Lo SH (2003) Inductive learning in less than one sequential data scan. JCAI’ 2003 (International Joint Conference on Artificial Intelligence)
• Fan W, Wang H, Lo SH, Yu PS, Stolfo S (2002) Progressive modeling. ICDM (International Conference on Data Mining) 2002
• Lo SH, Zheng T (2002) Backward haplotype transmission association (BHTA) algorithm—a fast multiple-marker screening method. Hum. Hered. 53 (4): 197-215.
• Gomez SM, Lo SH, Rzhetsky A (2001) Probabilistic prediction of unknown metabolic and signal-transduction networks. Genetics 159 (3): 1291-1298
• Chen K, Lo SH (1999) Case-cohort and case-control analysis with Cox's model. Biometrika 86 (4): 755-764
• Shane E, Rodino MA, McMahon DJ, Addesso V, Staron RB, Seibel MJ, Mancini D, Michler RE, Lo SH (1998) Prevention of bone loss after heart transplantation with antiresorptive therapy: a pilot study. Journal of Heart and Lung Transplantation 17 (11): 1089-1096
• Lo SH (1998) "Rao-Blackwell Theorem" in the Encyclopedia of Biostatistics (Editors-in-chief, Peter Armitage, Theodore Colton), John Wiley & Sons Ltd.
• Gershon AA, Mervish N, LaRussa P, Steinberg S, Lo SH, Hodes D, Fikrig S, Bonagura V, Bakshi S (1997) Varicella-zoster virus infection in children with underlying human immunodeficiency virus infecion. Journal of Infectious Diseases 176 (6): 1496-1500