Some good readings on important trends in statistical genetics
I. OVERVIEW
1. Science 7 November 2008: Vol. 322. no. 5903, pp. 881 - 888
Genetic Mapping in Human Disease
2. Nature Reviews Genetics 10, 241-251 (April 2009)
Human genetic variation and its contribution to complex traits
II. Association Studies, especially GWAS
3. Nature Reviews Genetics 9, 356-369 (May 2008)
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
4. Nature Reviews Cancer 4, 850-860 (November 2004)
Association studies for finding cancer-susceptibility genetic variants
III. Challenges of associations studies (interaction, population
stratification, etc)
5. Human Molecular Genetics, 2002, Vol. 11, No. 20 2463-2468
Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans
6. Nature Genetics 37, 1243 - 1246 (2005)
Population structure, differential bias and genomic control in a large-scale, case-control association study
IV. LD and Haplotype block
7. The American Journal of Human Genetics, Volume 69, Issue 1, 1-14, 1 July 2001
Linkage Disequilibrium in Humans: Models and Data
8. Nature Reviews Genetics 4, 587-597 (August 2003)
Haplotype blocks and linkage disequilibrium in the human genome
V. Selected methodology reviews
9. The American Journal of Human Genetics, Volume 78, Issue 3, 437-450, 1 March 2006
A Comparison of Phasing Algorithms for Trios and Unrelated Individuals
10. The American Journal of Human Genetics, Volume 74, Issue 5, 979-1000, 1 May 2004
Methods for High-Density Admixture Mapping of Disease Genes
posted by Tian @ 9:42 PM
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